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Highly skilled Help Desk Technician experienced with troubleshooting and resolving technical issues. Strong background in providing efficient and effective solutions to clients. Dedicated team player delivers great customer service.

Highly organized Front Desk Receptionist with exemplary multitasking, time management and customer service skills. Responsible professional willing to go extra mile to assist others with solving problems.

Apasionado por estar al día con las últimas tendencias y tecnologías en el campo del desarrollo web. Busco oportunidades emocionantes para aplicar mis habilidades y contribuir al éxito de proyectos desafiantes.

Talented Drafter with solid computer-aided design skills and familiarity with multiple industries. Generated accurate representations of solar plants, systems and components to meet client parameters. High-level technical skills and attention to detail enabled impressive results.

I am a dedicated professional with history of meeting company goals utilizing consistent and organized practices. Skilled in working under pressure and adapting to new situations and challenges to best enhance the organizational brand.

Hardworking and enthusiastic trained in every facet of successful work. Stays on top of current and expected demands, quickly realigning tasks to handle needs. Dedicated to first-rate communication and team success.

I have published several scientific papers:
GOSALBES, MJ., PÉREZ.-ARELLANO, I., ESTEBAN, CD., GALÁN, JL. PÉREZ-MARTÍNEZ, G.
Use of lac regulatory elements for gene expression in Lactobacillus casei.
2001, Le Lait 81:29-35.

PÉREZ-ARELLANO, I, ZUÑIGA, M., PEREZ-MARTINEZ, G. Construction of wide-host range vectors for the cloning of DNA fragments protected by transcriptional terminators.
2001, Plasmid 46, 106-116.

GIL M.TERESA,* PEREZ-ARELLANO, I *, BUESA J, PÉREZ-MARTÍNEZ, G.
* These authors have contributed equally.
Secretion of the vp8* protein in Lactococcus lactis.
2001, FEMS Microbiol Letters. 203, 269-274.

PEREZ-ARELLANO, I, PÉREZ-MARTÍNEZ, G.
Structural features of the lac promoter affecting gusA expression in Lactobacillus casei.
2002, Current Microbiology 45(3), 191-6.

PEREZ-ARELLANO, I, PÉREZ-MARTÍNEZ, G.
Optimisation of the green fluorescent protein (GFP) expression from a lactose-inducible promoter in Lactobacillus casei.
2003, FEMS Microbiol Letters 222 (1), 123-7.

PEREZ-ARELLANO I, GIL-ORTIZ F, CERVERA J, RUBIO V.
Glutamate-5-kinase from Escherichia coli: gene cloning, overexpression, purification and crystallization of the recombinant enzyme and preliminary X-ray studies.
2004, Acta Crystallogr D Biol Crystallogr. 60, 2091-4.

PEREZ-ARELLANO I, RUBIO V, CERVERA J.
Dissection of Escherichia coli glutamate 5-kinase: functional impact of the deletion of the PUA domain.
2005, FEBS Lett. 579(30):6903-8.

AIRES KA, CIANCIARULLO AM, CARNEIRO SM, VILLA LL, BOCCARDO E, PEREZ-MARTINEZ G, PEREZ-ARELLANO I, OLIVEIRA ML, HO PL.
Production of HPV-16 L1 Virus-Like Particles by recombinant Lactobacillus casei.
2006, Appl Environ Microbiol. 72(1):745-52.

PEREZ-ARELLANO I, RUBIO V, CERVERA J.
Mapping active site residues in glutamate-5-kinase. The substrate glutamate and the feed-back inhibitor proline bind at overlapping sites.
2006, FEBS Letters, 580, 6247-6253.

MARCO-MARÍN C, GIL-ORTIZ F, PEREZ-ARELLANO I, CERVERA J, FITA I AND RUBIO V.
A novel two domain architecture within the amino acid kinase family revealed by the crystal structure of Escherichia coli glutamate 5-kinase.
2007, J. Mol. Biol. 367, 1431–1446

PEREZ-ARELLANO I, GALLEGO J, CERVERA J.
The PUA domain - a structural and functional overview.
2007 FEBS J. 274, 4972-84.

PÉREZ-ARELLANO I, GOZALBO-ROVIRA R, MARTÍNEZ AI, CERVERA J.
Expression and purification of recombinant human MCT-1 oncogene in insect cells.
Protein J. 2010 Feb;29(2):69-74.

PÉREZ-ARELLANO I, CARMONA-ALVAREZ F, MARTÍNEZ AI, RODRÍGUEZ-DÍAZ J, CERVERA J.
Pyrroline-5-carboxylate synthase and proline biosynthesis: from osmotolerance to rare metabolic disease.
Protein Sci. 2010 Mar;19(3):372-82. Review.

PÉREZ-ARELLANO I, CERVERA J.
Glutamate kinase from Thermotoga maritima: characterization of a thermophilic enzyme for proline biosynthesis.
Extremophiles. 2010 Jul;14(4):409-15.


MARTÍNEZ AI, PÉREZ-ARELLANO I, PEKKALA S, BARCELONA B, CERVERA J.
Genetic, structural and biochemical basis of carbamoyl phosphate synthetase 1 deficiency.
Mol Genet Metab. 2010 Dec;101(4):311-23.
PÉREZ-ARELLANO I, CARMONA-ALVAREZ F, GALLEGO J, CERVERA, J.
Molecular mechanisms modulating glutamate kinase activity. Identification of the proline feedback inhibitor binding site. J Mol Biol. 2010, 404(5):890-901.


DÍEZ C, MARTÍNEZ AI, PEKKALA S, BARCELONA B, PÉREZ-ARELLANO I, SUMMAR M, RUBIO V, CERVERA J.
Molecular characterization of carbamoyl phosphate synthetase (CPSI) deficiency using human recombinant CPSI as a key tool.
Human Mutation, 2013 May 3. doi: 10.1002/humu.22349.

PÉREZ-ARELLANO I, SPINOLA-NAMIBIA M, BRAVO J.
Human Drg1 is a potassium dependent Gtpase activated by Lerepo4.
FEBS J. 2013 May 25. doi: 10.1111/febs.12356.

I have published a chapter of a scientific book:
MONEDERO V, PÉREZ-ARELLANO I, VIANA R, ZÚÑIGA M, BUESA J, MONTAVA R, RODRÍGUEZ-DÍAZ J, LEE HO P, SARNO DE OLIVEIRA L, Y PÉREZ-MARTÍNEZ G.
Diseño de probióticos como vectores de vacunas orales y otras moléculas terapéuticas. En: Microorganismos y salud. Bacterias lácticas y bifidobacterias probióticas. Book chapter 14, pág. 172-183. (Juan Miguel Rodríguez Gómez, Ed), Editorial Complutense, Madrid. (2007)

I am part of a patent:

GOSALBES SOLER MJ, PÉREZ ARELLANO I, ESTEBAN NIETO CD, GALÁN JL Y PÉREZ MARTÍNEZ G.
TITULO:
Uso de la secuencia de nucleótidos del promotor de la lactosa de lactobacillus casei para regular la expresión génica a través de una proteína antiterminadora.
Nº registro 2000-00897
PRIORITY COUNTRY SPAIN PRIORITY DATE 7 de Abril de 2000
ENTITY CSIC
OTHER COUNTRIES Europe

I have solved the 3D structure of a mutant enzyme of glutamate kinase without the PUA domain of Escherichia coli. PDB id: 2W21

-REDACTORA MÉDICA DEL ARTÍCULO:
As a medical writer I wrote the following paper: Maintenance therapy with vinflunine plus best supportive care versus best supportive care alone in patients with advanced urothelial carcinoma with a response after first-line chemotherapy (MAJA; SOGUG 2011/02): a multicentre, randomised, controlled, open-label, phase 2 trial. García-Donas J, Font A, Pérez-Valderrama B, Virizuela JA, Climent MÁ, Hernando-Polo S, Arranz JÁ, Del Mar Llorente M, Lainez N, Villa-Guzmán JC, Mellado B, Del Alba AG, Castellano D, Gallardo E, Anido U, Del Muro XG, Domènech M, Puente J, Morales-Barrera R, Pérez-Gracia JL, Bellmunt J. LANCET ONCOLOGY, 2017 May;18(5):672-681.


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