niger Search ResultsFull Names: Jacobus Pieter Hough
Surname: Van Wyk
Nationality: South African
Gender: Male (White)
ID no: 5806165053088
Cell number: 083 407 8621
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Top Skills Research: Title: Valorization of Biomass Waste for Medicinal Purposes.Description:The consumption of fossil fuels has an enormous negative effect on public health and the environment. Climate change and acid rain are visible examples of these negative environmental effects. Fossil fuels are not only consumed as a source of energy, but it is also a feedstock for the production of various medicines and pharmaceutical products. The reliance on this feedstock is not sustainable due to its finite nature, and its negative environmental impact classifies it as an undesirable component of any manufacturing, production, or synthetic procedure. It is of global importance that fossil fuels be replaced by alternative and renewable energy resources that could also be developed as feedstocks for many commodities and bio-products, such as medicines and pharmaceutical products.Lignocellulosic biomass is a perfect substance that could fulfill the role of a clean and environmentally friendly, feedstock that is also infinitely available. Examples of biomass include,* Wood biomass – wood shavings, sawdust and forestry residues.* Agricultural waste – rice straw, corn cob, corn straw, and sugarcane fiber* Sugar and starch, lignocellulosic material and wet biomass* Natural fiber waste such as hemp, flax, jute, and abaca* Energy crops such as fast-growing trees and switch grass* Aquatic biomass such as algae.Another biomass waste is substances originating from kitchens and gardens, with different forms ofwastepaper also contributing to the large amount of organic waste produced annually.Most of the ligno-cellulose-related developments done up to date are by the conversion of the cellulose component of biomass into biofuels such as bio-ethanol and the procedures applied during these actions include transesterification, gasification, pyrolysis, anaerobic digestion, and fermentation. The initial phase of these bio-conversion activities requires the cellulose component of biomass to be bio-converted into fermentable sugars such as glucose, a process mostly catalyzed by a hydrolytic enzyme known as cellulase. The cellulase used for the saccharification of lignocellulose comes from many fungal, bacterial, and plant origins and has been intensively researched, with the outcomes published widely in scientific literature by numerous scientists since 1970.A new value-added outcome of biomass waste that can benefit the medical sciences but has not yet been realized is the formation of renewable, sustainable, and biodegradable drug carriers. Firstly, will be the bioconversion of the lignocellulose component of biomass into lactic acid, which successively can be fermented into polylactic acid and finally be developed as a drug carrier system in association with co-polymers. Secondly is the preparation of nanocellulose from the lignocellulose section of biomass, which can also be developed as a drug carrier. Both polylactic acid and nanocellulose are non-toxic making them suitable materials to be introduced into a biological system. The third part of biomass waste development is the valorization of the medicinal value of phytochemicals in biomass waste. Obtaining information regarding this aspect would require the extraction of phytochemicals from biomass waste and determining its medicinal value in a biological system.Huge volumes of biomass waste, a major component of organic solid waste, are produced annually, which presents a significant management problem. Besides the land occupied by these discarded materials, its effect on the environment is also negative. An analysis of the biochemical composition of biomass waste revealed that it is a suitable resource that can be developed as a feedstock for producing biomaterials such as renewable drug carriers with the phytochemicals that can be valorized.Research Problem:The use of fossil fuels as an energy source and feedstock for the synthesis of medicines and pharmaceutical products, together with the accumulation of waste biomass, has detrimental effects on the environment. These effects can be limited by developing biomass waste as a resource of bioactive phytochemicals and renewable feedstock for drug carrier production.Scientific Publications: 1. T Motshologane and JPH van Wyk. Inhibitory Effects of Artemisia afra Extracts on the Bio-activity of Banana Tyrosinase. Online Journal of Biological Sciences, 25(1), 200 – 208, 2025.2. NA Ndukwe, JBM Seeletse and JPH van Wyk. Saccharification of Sawdust Materials at Different Incubation pH-values. Nature Environment and Pollution Technology, 24(1), 1 - 11, 2025.3. NA Ndukwe, JBM Seeletse and JPH van Wyk. Saccharification of Different Delignified Sawdust Masses from Various Trees Along the Lagos Lagoon in Nigeria. Nature Environment and Pollution Technology, 23(3), 1319 – 1332, 2024.4. JBM Seeletse, NA Ndukwe and JPH van Wyk. Temperature-related saccharification of various delignified sawdust materials from the Lagos Lagoon in Nigeria. Nature Environment and Pollution Technology, 23(2), 863 – 874, 2024.5. TM Ndlovu and JPH van Wyk. Saccharification of Various Wastepaper Materials by Cellulase from Brown Garden Snail (Cornu aspersum) at Different Incubation pH-values. Nature Environment and Pollution Technology. 22 (4): 2153 – 2162, 2023.6. JBM Sibiya, NA Ndukwe and JPH van Wyk. Development of sawdust from the Lagos Lagoon in Nigeria as a renewable feedstock for bio-product development. Journal of Biodiversity and Environmental Sciences, 18 (1), 25 – 32, 2021.7. KMP Mokatse, MAM Mogale and JPH van Wyk. The Influence of Trichoderma viride cellulase enzyme concentration on saccharification of wastepaper materials. Online Journal of Biological Sciences. 279 – 287, 2021.8. KMP Mokatse and JPH van Wyk. Physical and chemical pre-treatment of wastepaper to increase saccharification by Trichoderma viride cellulase. Global NEST Journal, 2021, 23 (2), 195 - 200.9. KMP Mokatse and JPH van Wyk. Successive Saccharification of Wastepaper as a Resource for Bio-product Development. Nature Environment and Pollution Technology, 20(3):1301, 2021.10. TM Ndlovu and JPH Van Wyk. Temperature dependent bioconversion of wastepaper by garden snaiwastepaperpersum) cellulase into glucose a feed stock for bio-product development. International Journal of Pharmaceutical Sciences and Research, 12(7):3985, 2021.11. K Rambau, KMP Mokatse and JPH van Wyk. Saccharification of Mixed Wastepaper for the Production of Fermentable Sugars as Feedstock for Bio-product Development. International Journal of Green and Herbal Chemistry. Vol 9 No 2, 174 – 183, 2020.12. Sibiya, J.B.M., Ndukwe, N.A. and Van Wyk, J.P.H. Saccharification of Sawdust Masses from the Lagos Lagoon in Nigeria with Aspergillus niger Cellulase. Pharmaceutical and Bioscience Journal. Vol 8(6), 24 – 31, 2020.13. N.A. Ndukwe, J.B.M. Sibiya, and J.P.H. van Wyk. Saccharification of Sawdust with Aspergillus niger cellulase. The Journal of Solid Waste Technology and Management. Vol 46 (3), 321 – 327, 2020.14. T.N. Ndlovu and J.P.H. van Wyk. Isolation of cellulase enzyme from brown garden snail (Cornu aspersum) for the saccharification of waste paper materials. MethodsX 6 (DOI: 10.1016/j.mex.2019.04.019), 1030 – 1035, 2019.15. K.M.P. Mokatse and J.P.H. van Wyk. The influence of substrate concentration on T. viride catalyzed saccharification of various waste paper materials. Bioscience Research. 16(3), 2927, 2019.16. B. Dhlamini and J.P.H. van Wyk. Successive saccharification of newspaper with A. niger cellulase. CPQ Microbiology Journal. 3:3, 1-10, 2019.17. T.M. Ndlovu and J.P.H. van Wyk. Relative saccharification of waste paper during successive treatment with garden snails (Cornu aspersum). Sustainable Chemistry and Pharmacy. Vol 11, 54 – 60, March 2019.18. N.A. Ndukwe, J.P.H. van Wyk, T. M. Mamabola, W. O. Okiei, B. I. Alo and C. C. Igwe. Bio-ethanol production from saccharified sawdust cellulose obtained from twenty different trees along the Lagos Lagoon in Nigeria. Bioscience Research. 15 (2), 1218 – 1224, 2018.19. J.P.H. van Wyk. SmarTTeaching Pharmacology. eLmL 2018 : The Tenth International Conference on Mobile, Hybrid, and On-line Learning, 54-57, 2018. pp20. T.M. Ndlovu and J.P.H. van Wyk. Saccharification of wastepaper with cellulase from garden snail (Cornu aspersum). International Journal of Environmental Science and Technology. 10.1007/s13762-018-1934-1, 2018.21. K.M.P. Mokatse and J.P.H. van Wyk. Identification and optimum incubation temperature for saccharification of various wastepaper materials by cellulose from Trichoderma viride. Bioscience Research, 2017, 14 (4), 1269 – 1278.22. K.M.P. Mokatse and J.P.H. van Wyk. Temperature values for optimum saccharification of various wastepaper materials by cellulase from Trichoderma viride. Bioscience Research, Innovative Scientific Information & Service Network. 14 (4), 1269 – 1278, 2017.23. K.M.P. Mokatse and J.P.H. van Wyk. pH-Values for optimum saccharification of various wastepaper materials by cellulase from Trichoderma viride. Journal of Basic and Applied Scientific Research. 7 (9), 18 – 26, 2017.24. J.B.M. Sibiya and J.P.H. van Wyk. Bioconversion of waste newspaper into fermentable sugars at different temperatures with different Aspergillus Niger cellulase concentrations. Journal of Applied Biology and Biotechnology. Vol. 4 (4), 69 – 74, 2016.25. K.M.P. Mokatse, H.S. Mhalanga and J.P.H. van Wyk. Relative saccharification and initial degradation rates of different waste paper materials by cellulase from Trichoderma viride for bioenergy development. Journal of Applied Bio-sciences. Vol 105, 10183 – 10190, 2016.26. J.P.H. van Wyk and JBM Sibiya. Relative and efficient saccharification of waste office paper by different concentrations of Aspergillus Niger cellulase at various temperatures. International Journal of Innovation and Scientific Research. Vol. 23, (1), 1-9, 2016.27. K.M. Mokatse and J.P.H. van Wyk. Cellulase Catalyzed Bioconversion of Different Wastepaper Materials into Fermentable Sugars. International Journal of Biosciences. Vol. 8, (2), 66-76, 2016.28. J.P.H van Wyk, J. B.M. Sibiya, R.B. Dhlamini. Saccharification and Change of Incubation pH during the bioconversion of various wastepaper materials with cellulase from Aspergillus Niger. International Journal of Pure and Applied Biosciences. Vol 3 (6), 12 – 20, 2015.29. K.M. Mokatse and J.P.H. van Wyk. Relative saccharification of various wastepaper materials by cellulose from Aspergillus Niger. European Journal of Biotechnology and Biosciences. Vol. 3 (8), 44 – 46, 2015.30. J.P.H. van Wyk, and J.B.M. Sibiya. Saccharification of ink covered office paper by different concentrations of cellulase from Trichoderma viride. Journal of Chemical and Pharmaceutical Research. Vol 6 (10): 9 – 17, 2014.31. J.P.H. van Wyk, and J.B.M. Sibiya. Effect of ink on the saccharification of waste office paper during the biodegradation with cellulase from Trichoderma viride at different temperatures. International Research Journal of Biological Sciences. Vol 3 (8): 40 – 45, 2014.32. J.P.H. van Wyk and T. M. Mamabolo. The relative saccharification of different masses of waste paper materials into fermentable sugars by Trichoderma viride cellulase. International Journal of Biotechnology and Allied Fields (IJBAF). Vol 1(4): 210 – 222, 2013.A. Ndukwe, W.O. Okiei, B.I. Alo, J.P.H. van Wyk, T.M. Mamabolo and C.C. Igwe. (2013) Enzymatic bioconversion of Kraft pulped and oxidative delignified sawdust from the Lagos Lagoon, Nigeria into fermentable sugars. Scientific Research and Essays. Vol 8(13). pp 493 – 500, 2013.33. N. A. Ndukwe, W. O. Okiei, B. I. Alo, J.P.H. van Wyk, T. M. Mamabolo and C. C. Igwe. Glucose formation during biodegradation of Kraft-pretreated lignocellulosic waste. International Journal of Environment and Bioenergy. Vol. 5 (3) 156 – 163, 2013.34. N. A. Ndukwe, W. O. Okiei, B. I. Alo, J.P.H. van Wyk, T. M. Mamabolo and C. C. Igwe. Saccharification of delignified sawdust from twenty different trees in the Lagos area of Nigeria. African J Biotechnology. Vol. 11(100) 16625 – 16629, 2012.35. J.P.H. van Wyk, Biowaste as a Resource of Bioproduct Development. Survival and Sustainability, Environmental Earth Sciences, p 875 – 883, 2011. Springer-Verlag Berlin, Heidelberg.36. L. Brown, O. Heyneke, D. Brown, J.P.H. van Wyk, J.H. Hamman. Impact of traditional medicinal plant extracts on antiretroviral drug absorption. Journal of Ethnopharmacology, Vol 119 (3), 588-592, 2008.37. J.P.H. van Wyk and M. Mohulatsi. Biodegradation of waste cellulose. Journal of Polymers and the Environment. Vol. 11 (1) 23 – 28, 2003.J.P.H. van Wyk and M. Mohulatsi. Biodegradation of waste cellulose by cellulase from Trichoderma viride. Bioresource Technology. Vol. 86, 21 – 23, 2003.38. J.P.H. van Wyk. Bio-development of wastepaper as a resource of renewable energy: Influence of enzyme concentration and paper amount on the bioconversion process. Energy and Fuels. Vol. 16 (5), 1277 – 1279, 2002.39. J.P.H. van Wyk. Biotechnology and the utilization of Biowaste as a Resource for Renewable Development. World Conference on Technology Advances for Sustainable Development. Conference Proceedings. Cairo, Egypt, 2002.40. J.P.H. van Wyk and Legoale, P.B. Saccharification of wastepaper mixtures with cellulase from Penicillium funiculosum. Biotechnology Letters. Vol 23 (22), 1849 – 1852. 2001.41. J.P.H. van Wyk. Utilization of used biomass for renewable bio-energy development. Sharjah Solar Energy Conference. Conference Proceedings. Sharjah, U.A.E., 2001.42. J.P.H. van Wyk. Sequential bioconversion of used paper to sugars by cellulases from Trichoderma reesei and Penicillium funiculosum. The Environmentalis. Vol 21(3), 211 – 220, 2001.43. J.P.H. van Wyk. A Review: Biotechnology and the utilization of organic waste as a resource for bioproduct development. Trends in Biotechnology. Vol 19 (5), 172 -177, 2001.44. J.P.H. van Wyk and M. Mohulatsi. Utilization of used paper materials as a renewable resource for bioproduct development. Australian Biotechnology. Vol 11(5), 38 – 40, 2001.45. J.P.H. van Wyk, A.M. Mogale and T.A. Seseng. Bioconversion of wastepaper to sugars by cellulase from Aspergillus niger, Trichoderma viride and Penicillium funiculosum. The Journal of Solid Waste Technology and Management. Vol. 27(2), 82 – 86, 2001.46. J.P.H. van Wyk. Conversion of Used Paper Materials into Sugars: A Biochemical Process to Limit Environmental Pollution. The Chemical Educator. Vol 5 (6), 315 – 316, 2000. 47. J.P.H. van Wyk. Wastepaper as a resource of Bioenergy. Renewable Energy, Renewables: The Energy for the21st Century. World Renewable Energy Congress VI, Brighton UK. Part II, 1336 – 1339, 2000.48. J.P.H. van Wyk. Wastepaper as a resource of Bioenergy. Biocycle International: Journal of Composting and Recycling. Vol 41 (2), 80, 2000.49. J.P.H. van Wyk, Mogale, M.A. & Seseng, T. E. Saccharification of used paper with different cellulases. Biotechnology Letters. Vol 22 (6), 491 – 494, 2000.50. J.P.H. van Wyk and A.M. Mogale. Increased saccharification of pretreated used paper materials by Trichoderma reesei and Aspergillus niger cellulase mixtures and catalytic profiles of the individual enzymes. Resource and Environmental Biotechnology. Vol 3, 71 – 79, 2000.51. J.P.H. van Wyk. Increased bioconversion of pretreated wastepaper to sugars by successive treatment with cellulase from Penicillium funiculosum and Trichoderma reesei. Australasian Biotechnology. Vol 9 (4), 206 – 210, 1999.52. J.P.H. van Wyk, A., M. Mogale and S. K. Moroka. Bioconversion of waste paper materials to sugars: an application illustrating the environmental benefit of enzymes. Biochemical Education. Vol 27, (4), 47 – 49, 1999. pp53. J.P.H. van Wyk. The Sweet Taste of Paper. Archimedes. Vol 41 (2), 14 – 16, 1999.54. J.P.H. van Wyk. Hydrolysis of pretreated paper materials by different concentrations of cellulase from Penicillium funiculosum. Bioresource Technology. Vol 69, (3), 269 - 273, 1999.55. J.P.H. van Wyk. Saccharification of paper products by cellulase from Penicillium funiculosum and Trichoderma reesei. Biomass and Bioenergy. Vol 16, (3), 239 – 242, 1999.56. J.P.H. van Wyk. Cellulase catalyzed hydrolysis of paper materials: pH and temperature profiles. Resource and Environmental Biotechnology: Vol 2, (3), 249 -254, 1999.57. J.P.H. van Wyk and A.M. Mogale. Saccharification of paper materials by mixtures of cellulase from Penicillium funiculosum and Aspergillus niger. Australasian Biotechnology. Vol 8 (6), 357 – 359, 1998.58. J.P.H. van Wyk. Paper hydrolysis by cellulase from Penicillium funiculosum and Trichoderma viride. Bioresource Technology. Vol 63 (3) 275 – 277, 1998.59. J.P.H. van Wyk and Anita C. Botha. Introduction to Organic Chemistry. Willow Publishers, Pretoria. ISBN : 0-620-21554-2, 1997.60. J.P.H. van Wyk and Anita C. Botha. Hydrolysis of cellulose materials during successive treatment with cellulase from Penicillium funiculosum. Biotechnology Letters. Vol 19 (7), 687 – 689, 1997.61. J.P.H. van Wyk. Cellulose adsorption-desorption and cellulose saccharification during enzymatic hydrolysis of cellulose materials. Biotechnology Letters. Vol 19 (8), 775 – 778, 1997.62. J.P.H. van Wyk. Thermostability of cellulase from Penicillium funiculosum. Biotechnology Techniques. Vol 11 (6), 385 – 386, 1997.63. J.P.H. van Wyk. Cellulose hydrolysis and cellulase adsorption after pre-treatment of cellulose material. Biotechnology Techniques. Vol 11 (6), 443 – 445, 1997.Conference Participation: 1. Oral Presentation: Smartteaching Pharmacology.53 Annual Conference of the South African Society for Basic and Clinical Pharmacology Research.5 – 7 October 2019.Pretoria, South Africa.Oral Presentation: Smart-teaching Pharmacology.2. The Tenth International Conference on Mobile, Hybrid and On-line Learning.March 25 – 29, 2018.Rome, Italy.Oral Presentation: Green Pharmacology – More than only Medicine.3. All Africa Congress on Pharmacology and Pharmacy.5 – 8 October, 2016.Johannesburg, South Africa.Oral Presentation: Development of Waste Cellulose as a Resource of Bioenergy.4. The European Conference on Sustainability.1 – 3 July, 2013.Brighton, UK.Oral Presentation: Development of Waste Cellulose as a Resource of Bio-energy.5. The First United Arab Emirates Conference on Pure and Applied Chemistry.1 – 3 March, 2011.6. International Conference on Sustainability and Environment: Survival and Sustainability.19 – 24 Februamerican University of Sharjah, UAE.Oral Presentation: Biowaste as a Resource of Bioproduct Development.ry, 2007.Nicosia, CyprusOral Presentation: Biotechnology and the Utilization of Biowaste as a Resource for Renewable DevelopmentSecond World Conference on Technology Advances for Sustainable Development and Renewable Energy.20 – 22 March, 2002.Cairo, Egypt.Oral Presentation: Utilization of Used Biomass for Renewable Bio-energy Development.Sharjah Solar Energy Conference.19 – 22 February 2001.University of Sharjah, Sharjah, UAE.Poster Presentation: Waste Paper as Resource of Bio-energy.Renewable Energy, Renewables: The Energy of the 21 Century.World Renewable Congress VI.7 – 10 July, 2000.Brighton, UK.Reviewer of Scientific Journals:Online Journal of Biological Sciences.Bioresource Technology.International Journal of Recycling Organic Waste.Waste Management.Journal of Biotechnological Sciences.Research in Pharmaceutical Biotechnology.South African Journal of Pharmaceutical Sciences.Journal of Toxicology and Environmental Health Sciences.African Journal of Pharmacy and Pharmacology.Process Biotechnology.International Journal of Medicine and Medical Sciences.Asian Journal of Microbiology.Journal of Energy Research and Reviews.Scientific Techniques:High-Pressure Liquid Chromatography.Electrophoresis.Low-Pressure Liquid Chromatography.Column Chromatography.Spectrophotometric Analyses.General laboratory techniques related to enzymology.Recent Post-graduate Student Output:PhD - 2MSc - 10PhD registered (2025) - 1MSc registered (2025) - 3 Show More
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Top Skills Bilingue – anglais et français Domaines techniques d’expertises : modélisation hydro-climatique, hydrologique et hydrogéologique couplée à la télédétection; conception des solutions d’adaptation et résilience aux changements climatiques (dans les secteurs agroforestiers/agrosylvopastoraux) fondées sur les connaissances scientifiques, les savoirs expérientiels et les savoirs locaux des communautés autochtones ; conception des systèmes d’irrigation, d’ouvrages hydrauliques d’adduction d’eau potable et assainissement; gestion intégrée des ressources en eau; protection de l’environnement, agriculture durable; planification, gestion et suivi-évaluation des projets et programmes multilatéraux et bilatéraux Parfaite connaissance des outils de la gestion axée sur le résultat Excellente connaissance des fonctionnements et des institutions et administrations publiques en Afrique de l’Ouest et particulièrement au Niger (ancien travailleur des ministères de l’environnement et de l’Hydraulique du Niger) Excellente connaissance des problématiques induites par les effets des changements climatiques en Afrique de l’Ouest et particulièrement au Niger dans les secteurs du développement économique, l’agriculture, la santé, l’accès à l’eau et la gestion foncière Certifications Certification en Gestion projet :Trait d’union/Montréal, Canada Show More
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