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Summary
Overview
Work History
Education
Skills
Additional Information
Publications
Timeline

Shao-Yung Chen

Ph.D. Candidate Of Chemical And Biomolecular Engineering
Baltimore
Summary

Deadline-driven Analytical Chemist demonstrating superior quality assurance and accuracy in recording results. Astute professional with exceptional usage of analytical techniques, including large scale global-, glyco-, and phospho-proteomics, and extensive knowledge of mass spectrometry-based data dependent acquisition (DDA) and data independent acquisition (DIA). Ready to join a new organization collaborating with other professionals in a laboratory environment.

Overview
7
7
years of post-secondary education
8
8
years of professional experience
Work History

Ph.D. Candidate

Johns Hopkins Medical Institute
2018-04 - Current
  • Developed high-throughput intact glycopeptide enrichment for site specific glycasylation analysis.
  • Processed large scale urinary global and glycoproteomics data
  • Developed a label-free data-dependent glycopeptide quantification and recovery software: GPQuant

Undergraduate Research assistant

National Taiwan University
2014-02 - 2017-06
  • Fabricated human keratin crosslinked with chitosan composite film for bone tissue engineering.
  • Fabricated glycol chitosan and gelatin hydrogel for chondrongenic differentiation.

Taipei branch research intern manager

Shiny Chemical Industrial Co
2015-10 - 2017-02
  • Conducted cell characteristic tests.
  • Conducted melanin inhibition evaluation of nano-diamond materials.
  • Conducted graphene surface characteristic testing.
Education

Ph.D. Chemical and Biomolecular Engineering

Johns Hopkins University (JHU)
2017-08 - Current

Bachelor of Science Chemical Engineering

National Taiwan University (NTU)
2013-09 - 2017-06
Skills

Large Scale Mass Spectrometry Based Proteomics Sample Preparation

Glyco-proteomics Capturing Technique/ Sample Enrichment Technique

Computer Languages: Maplesoft, Python

LC-MS/MS Data Acquisition and Instrument Maintenance

DIA Proteomics

English Writing/Communication Skills

Additional Information
  • 2013-2015 Scholarship (4x) for Excellent Academic Performance of Government Employee's Children (Taiwan)
  • 2016 Annual American Institute of Chemical Engineers, Student Poster Competition, 1st place in Food, Pharmaceutical and Biotechnology (San Francisco)
  • 2019 Young Investigator Travel Awards, Washington-Baltimore Mass Spectrometry Discussion Group (Maryland)
Publications

1. Chen, S. Y., Dong, M., Yang, G., Zhou, Y., Clark, D. J., Lih, T. M., Schnaubelt, M., Liu, Z., & Zhang, H. (2020). Glycans, Glycosite, and Intact Glycopeptide Analysis of N-Linked Glycoproteins Using Liquid Handling Systems. Analytical Chemistry, 92(2), 1680–1686.

2. Clark, D. J., Hu, Y., Schnaubelt, M., Fu, Y., Ponce, S., Chen, S. Y., Zhou, Y., Shah, P., & Zhang, H. (2019). Simple Tip-Based Sample Processing Method for Urinary Proteomic Analysis. Analytical Chemistry, 91(9), 5517–5522.

3. Dong, M., Mamie Lih, T., Chen, S. Y., Cho, K. C., Eguez, R. V., Höti, N., Zhou, Y., Yang, W., Mangold, L., Chan, D. W., Zhang, Z., Sokoll, L. J., Partin, A., & Zhang, H. (2020). Urinary glycoproteins associated with aggressive prostate cancer. Theranostics, 10(26), 11892–11907.

4. Yang, G., Höti, N., Chen, S.-Y., Zhou, Y., Wang, Q., Betenbaugh, M., & Zhang, H. (2020). One-Step Enrichment of Intact Glycopeptides From Glycoengineered Chinese Hamster Ovary Cells. Frontiers in Chemistry, 8, 240.

5. Zhou, Y., Lih, T. M., Pan, J., Höti, N., Dong, M., Cao, L., Hu, Y., Cho, K. C., Chen, S. Y., Eguez, R. V., Gabrielson, E., Chan, D. W., Zhang, H., & Li, Q. K. (2020). Proteomic signatures of 16 major types of human cancer reveal universal and cancer-type-specific proteins for the identification of potential therapeutic targets. Journal of Hematology and Oncology, 13(1), 1–15.

6. Zhou, Y., Lih, T. S. M., Yang, G., Chen, S. Y., Chen, L., Chan, D. W., Zhang, H., & Li, Q. K. (2020). An Integrated Workflow for Global, Glyco-, and Phospho-proteomic Analysis of Tumor Tissues. Analytical Chemistry, 92(2), 1842–1849.

Timeline

Ph.D. Candidate

Johns Hopkins Medical Institute
2018-04 - Current

Ph.D. Chemical and Biomolecular Engineering

Johns Hopkins University (JHU)
2017-08 - Current

Taipei branch research intern manager

Shiny Chemical Industrial Co
2015-10 - 2017-02

Undergraduate Research assistant

National Taiwan University
2014-02 - 2017-06

Bachelor of Science Chemical Engineering

National Taiwan University (NTU)
2013-09 - 2017-06