Innovative Researcher adept at developing probing questions, designing experiments and generating meaningful results. Experienced at identifying and using new technologies and resources. Works effectively and collaboratively with teams and individuals.
2022 Helge Ax:son Johnsons Stiftelsen (25 000 SEK)
Project title – Electrochemical redox toolbox for selective C-H activation reactions
2021 Wenner-Gren Foundation (20 500 SEK)
Project title: Electrochemical C-H annulation of pyrazoles with alkynes
2021 Crafoord Foundation (200 000 SEK)
Project title: Non-classical organic synthesis through C-H activation reactions
2019 Crafoord Fondation (200 000 SEK)
Project title: New methods and concepts for catalyzed organic synthesis
2019 Helge Ax:son Johnsons Stiftelsen (50 000 SEK)
Project title: Strategies for reductive trifluoromethylation of Nitroarenes
2018 Wenner-Gren Foundation (22 500 SEK)
Project title: Copper catalyst and electricity for C-N bond formation
2018 RISE institute (200 000 SEK)
Project title: Development of novel antifouling compound from Selectopeâ
2017 Wenner-Gren Foundation (25 000 SEK)
Project title: Robust cobalt catalyzed intramolecular C-H activation
2017 Helge Ax:son Johnsons Stiftelsen (28 000 SEK)
2016 Helge Ax:son Johnsons Stiftelsen (30 000 SEK)
Project title: Cobalt catalysed C-H activation with 1,3-diynes
2015 Wenner-Gren Foundation (12 000 SEK)
Project title: Rhodium and copper catalyzed N-arylation through chelation assistance
2014 ÅForsk Foundation (15 000 SEK)
Project title: Rhodium catalyzed aerobic C(sp2)-C(sp) dehydrogenative aminoarylation of alkynes to highly functionalized indoles from N-arylurea under mild conditions
2009 CSIR-SRF Award (2 year stipend for PhD studies)
2008 UGC Award (1 year stipend for PhD studies)
2008 DST Award (6 month stipend for PhD studies)
2004 A. L. Mudaliyar Scholarship (5000 INR)
Hobbies & Interests
Peer reviewed original articles
54. S. Kathiravan,* I. A. Nicholls. Recent advances in electrochemical C-N bond formation via C-H/N-H activation with hydrogen evolution. Current research in Green and Sustainable Chemistry, 2024, 8, 100405. (Invited contribution)
53. S. Kathiravan,* T. Zhang, I. A. Nicholls. Iridium catalysed C2 site-selective methylation of indoles using pivaloyl directing group through weak chelation-assistance. RSc Advances 2023,13, 11291-11295.
52. S. Kathiravan,* P. Anaspure. Electrochemical rhodium catalysed alkyne annulation with pyrazoles through anodic oxidation –a metal oxidant/additive free methodology. Organic & Biomolecular Chemistry, 2023, 21, 2024-2033.
51. P. Dhillon, P. Anaspure, J. G. Wiklander, S. Kathiravan, I. A. Nicholls. Diyne-steered switchable regioselectivity in cobalt(II)-catalyzed C(sp2)-H activation of amides with unsymmetrical 1,3-diynes. Organic & Biomolecular Chemistry, 2023, 21, 1942-1951.
50. S. Kathiravan,* P. Anaspure, T. Zhang, I. A. Nicholls. Tandem iridium-catalysed decarbonylative C-H activation of indole: Sacrificial electron rich ketone assisted bis-arylsulfenylation. Organic Letters, 2021, 23, 3331-3336.
49. S. Kathiravan,* I. A. Nicholls. Cobalt-catalyzed oxidative annulation of benzothiophene-[b]-1,1-dioxide through diasteroselective double C-H activation. Organic Letters, 2019, 21, 9806-9811.
48. S. Kathiravan,* S. Subramanian, I. A. Nicholls. Electrooxidative amination of sp2 C-H bonds: Coupling of amines with aryl amides via copper catalysis. Organic Letters, 2019, 21, 1968-1972.
47. S. Suriyanarayanan, G. D. Olsson, S. Kathiravan, N. Ndizeye, I. A. Nicholls. Non-ionic deep eutectic liquids: Acetamide urea derived room temperature solvents. International Journal of Molecular Sciences, 2019, 20.
46. S. M. E. Nilsson, S. Suriyanarayanan, S. Kathiravan, J. Yli-Kauhaluoma, T. Kotiaho, Enantioselective hyperporous molecularly imprinted thin flim polymers. RSc Advances, 2019, 9, 33653-33656.
45. S. Kathiravan, I. A. Nicholls. Cobalt catalysed, regioselective C(sp2)-H activation of amides with 1,3-diynes. Organic Letters, 2017,19, 4758-4761.
44. S. Kathiravan, I. A. Nicholls. Monoprotected L-amino acid (L-MPAA), accelerated bromination, chlorination, and iodination of C(sp2)-H bonds by iridium(III) catalysis. Chemistry European Journal, 2017, 23, 7031-7036.
43. S. Kathiravan, I. A. Nicholls. Palladium catalysed vinyltrifluoromethylation of aryl halides through decarboxylative cross coupling with 2-(trifluoromethyl)acrylic acid. Organic Letters, 2015, 17, 1874-1877. (One of most read articles in April 2015)
42. S. Kathiravan, S. Ghosh, G. Hogarth, I. A. Nicholls. Copper catalysed amidation of aryl halides through chelation assistance. Chemical Communications, 2015, 51, 4834-4837. (One of most read articles in February 2015)
41. S. Kathiravan, I. A. Nicholls. Rhodium(III)-catalysed aerobic synthesis of highly functionalized indoles from N-arylurea under mild conditions through C-H activation. Chemical Communications, 2015, 50, 14964-14967. (One of most read articles in November 2014)
40. S. Kathiravan, I. A. Nicholls. Rhodium(III) catalyzed, redox-neutral C(sp2)-H alkenylation using pivalimide as a directing group with internal alkynes. Tetrahedron Letters, 2017, 58, 1-4.
39. S. Kathiravan, I. A. Nicholls. Rhodium catalysed oxidative perfluoroalkenylation by carbonyl group directed C-H bond activation. European Journal of Organic Chemistry, 2014, 7211-7219.
38. S. Kathiravan, R. Raghunathan. Expedient synthesis of novel ferrocenyl spiropyrrolidines through 1,3-dipolar cycloaddition reaction. Journal of Heterocyclic Chemistry, 2014, 51, 906-910.
37. S. Kathiravan, R. Raghunathan. Synthesis of pyrrolo[2,3-a]pyrrolizidino derivatives through intramolecular 1,3-dipolar cycloaddition in ionic liquid medium. Synthetic Communications, 2013, 147-155.
36. S. Kathiravan, R. Raghunathan. Novel one pot regioselective multicomponent synthesis of highly functionalized spiropyrrolidines through 1,3-dipolar cycloaddition. Synthetic Communications, 2013, 1041-1054.
35. S. Kathiravan, R. Raghunathan, G. Suresh, G. V. Siva. Synthesis and antimicrobial activities of novel ferrocenyl dispiropyrrolidines and Pyrrolizidines. Medicinal Chemistry Research, 2012, 21, 3170-3176.
34. S. Kathiravan, R. Raghunathan. Synthesis of naphtho[2,1-b]pyrano pyrrolothiazole derivatives through 1,3-dipolar cycloaddition reaction. Synthetic Communications. 2012, 3068-3076.
33. S. Kathiravan, A. R. Suresh Babu, R. Raghunathan. Clean and expedient synthesis of Pyrido[1,4]oxazepino spiropyrrolidines through one-pot three component [3+2] cycloaddition reactions. Synthetic Communications, 2010, 3721-3727.
32. S. Kathiravan, R. Raghunathan. Expedient synthesis of highly functionalized coumarin derivatives through a domino Reaction. Synlett, 2010, 1927-1930.
31. S. Kathiravan, R. Raghunathan. Novel synthesis of naphtha[2,1-b]pyrano pyrrolizidines and indolizidines through intramolecular 1,3-dipolar cycloaddition reaction. Tetrahedron Letters, 2010, 51, 3065-3070.
30. S. Kathiravan, R. Raghunathan. Expedient synthesis of N-fused indoles through an intramolecular [3+2]-cycloaddition approach. Synlett, 2010, 952-954.
29. S. Kathiravan, R. Raghunathan. A facile one-pot three-component synthesis of macrocyclic imidazolidines by [3+2]cycloaddition reaction of azomethine ylides. Synlett, 2009, 1126-1130.
28. S. Kathiravan, R. Raghunathan. A facile one-pot three-component synthesis of ferrocene-grafted dispiropyrrolidine/pyrrolizidine scaffolds through -[3+2] cycloaddition reaction of ferrocenyl Baylis-Hillman adduct. Tetrahedron Letters, 2009, 50, 6116-6120.
27. S. Kathiravan, E. Ramesh, R. Raghunathan. Synthesis of pyrrolo[2,3-a]pyrrolizine and pyrrolizine[2,3-a]pyrrolizine derived from allyl derivatives of Baylis-Hillman adducts through intramolecular 1,3-dipolar cycloaddition. Tetrahedron Letters, 2009, 50, 2389-2391.
X-Ray crystallography publications
26. S. Selvanayagam, B. Sridhar, S. Kathiravan, R. Raghunathan. Methyl (2Z)-2-[(2-formyl-3-methyl-1H-indol-1-yl)methyl]-3-(4-methoxyphenyl)-prop-2-enoate. Acta Cryst. 2014, E70, 431-432.
25. S. Selvanayagam, K. Ravikumar, S. Kathiravan, R. Raghunathan. 2-[(Ferrocen-1-yl)(hydroxy)methyl]prop-2-enenitrile. Acta Cryst. 2013, E69, 669.
24. B. Gunasekaran, S. Kathiravan, R. Raghunathan, V. Manivannan. Synthesis and crystal structure of methyl 9-(4-Methoxyphenyl)-8a,9,9a,10,11,12,13,14a-octa hydro-8H-benzo[f]chromeno[3,4-b]indolizine-8a-carboxylate. Asian Journal of Chemistry, 2013, 25, 51-54.
23. S. Selvanayagam, B. Sridhar, S. Kathiravan, R. Raghunathan. Methyl-9-(4-methoxyphenyl)-19-methyl-3,12-diazapentacyclo[10.7.0.0,2,10.03,8.013,18]nonadeca-1(19),13(18),14,16- tetraene-10-carboxylate. Acta Cryst. 2013, E69, 776.
22. B. Gunasekaran, S. Kathiravan, R. Raghunathan, V. Manivannan. 19-Ferrocenyl-18-oxa-8,16-diazapenta-cyclo[8.6.3.01,10.02,7.012,16]nonadeca-2(7),3,5-triene-9,17-dione. Acta Cryst. 2010, E66, 1543.
21. S. Selvanayagam, B. Sridhar, K. Ravikumar, S. Kathiravan, R. Raghunathan. Methyl-3-[(1H-benzimidazol-1-yl)methyl]-1-methyl-4-(4-methylphenyl)-2′- oxopyrrolidine-2-spiro-3′-1-benzimidazole-3-carboxylate. Acta Cryst. 2010, E66, 2508-2509.
20. S. Selvanayagam, B. Sridhar, K. Ravikumar, S. Kathiravan, R. Raghunathan. Crystal structure of 1-(propa-1,2-dienyl)-1H-benzo(d)imidazole-2-carbaldehyde. Acta Cryst. 2010, E66, 59-60.
19. S. Selvanayagam, B. Sridhar, K. Ravikumar, S. Kathiravan, R. Raghunathan. Methyl 4-(4-Chlorophenyl)-3,3a,4,4a,5,12c-hexahydro-2-thianaphtho- [1′,2′:3,2]furo[5,4-b]pyrrolizine-4a-carboxylate. Acta Cryst. 2010, E66, 2098.
18. S. Selvanayagam, B. Sridhar, K. Ravikumar, S. Kathiravan, R. Raghunathan. Methyl-4-phenyl-1,2,3,3a,4,4a,5,12c-octa-hydronaphtho[1′,2′:3,2]furo[5,4- b]pyrrolizine-4a-carboxylate. Acta Cryst. 2010, E66, 1345.
17. S. Thenmozhi, A. Subbiahpandi, S. Kathiravan, R. Raghunathan. Methyl 3-(4-methoxy-phen-yl)-1-methyl-1,2,3,3a,4,11b-hexa-hydro-benzo[f]chromeno[4,3-b]pyrrole-3a-carboxyl-ate. Acta Cryst. 2010, E66, 893.
16. B. Gunasekaran, S. Kathiravan, R. Raghunathan, V. Manivannan. Methyl 4-(4-chloro-phen-yl)-1,2,3,3a,4,4a,5,12c-octa-hydro-benzo[f]chromeno[3,4-b]pyrrolizine-4a-carboxyl-ate. Acta Cryst. 2010, E66, 810-811.
15. B. Gunasekaran, S. Kathiravan, R. Raghunathan, V. Manivannan. Methyl 3-(4-chlorophenyl)-1-methyl-1,2,3,3a,4,11c-hexahydrobenzo[f]chromeno[4,3-b]pyrrole-3a-carboxylate. Acta Cryst. 2010, E66, 611-612.
14. B. Gunasekaran, S. Kathiravan, R. Raghunathan, V. Manivannan. 4′-Ferrocenyl-1′-methylacenapthylene-1-spiro-2′-pyrrolidine-3′-spiro-2′′-indane-2,1′′,3′′(1H)-trione. Acta Cryst. 2009, E65, 1673.
13. B. Gunasekaran, S. Kathiravan, R. Raghunathan, G. Chakkaravarthi, V. Manivannan. Methyl-9-p-tolyl-8a,9,9a,10,11,12,13,14a-octahydro-8H-benzo[f]chromeno[3,4-b]indolizine-8a-carboxylate. Acta Cryst. 2009, E65, 3188.
12. B. Gunasekaran, S. Kathiravan, R. Raghunathan, G. Chakkaravarthi, V. Manivannan. Methyl-9-(4-bromo-phen-yl)-8a,9,9a,10,11,12,13,14a-octa-hydro-8H-benzo[f]chromeno[3,4-b]indolizine-8a-car-box-ylate. Acta Cryst. 2009, E65, 2550.
11. S. Nirmala, E. T. S. Kamala, L. Sudha, S. Kathiravan, R. Raghunathan. Methyl 1-methyl-3-p-tolyl-1,2,3,3a,4,11c-hexa-hydro-benzo[f]chromeno[4,3-b]pyrrole-3a-carboxyl-ate. Acta Cryst. 2009, E65, 1811.
10. E. T. S. Kamala, S. Nirmala, L. Sudha, S. Kathiravan, R. Raghunathan. Methyl 5-phenyl-1,2,3,4,4a,5,5a,13c-octahydro-6H-benzo[f]chromeno[3,4-b]indolizine-5a-carboxyl-ate. Acta Cryst. 2009, E65, 1923-1924.
9. S. Nirmala, E. T. S. Kamala, L. Sudha, S. Kathiravan, R. Raghunathan. Methyl 4-(4-methoxy-phen-yl)-1,2,3,3a,4,4a,5,12c-octa-hydro-benzo[f]chromeno[3,4-b]pyrrolizine-4a-carboxyl-ate. Acta Cryst. 2009, E65, 1938.
8. S. Nirmala, E. T. S. Kamala, L. Sudha, S. Kathiravan, R. Raghunathan. Methyl 3-(4-bromo-phen-yl)-1-methyl-1,2,3,3a,4,9b-hexa-hydro-benzo[f]chromeno[4,3-b]pyrrole-3a-carboxyl-ate. Acta Cryst. 2009, E65, 2028-2029.
7. B. Gunasekaran, S. Kathiravan, R. Raghunathan, V. Renuga, V. Manivannan. 6-Phenyl-5a,6,6a,7,12,13a-hexa-hydro-5H-benzo[6,7]indolizino[3,2-a]pyrrolizine. Acta Cryst. 2009, E65, 1454.
6. E. T. S. Kamala, S. Nirmala, L. Sudha, S. Kathiravan, R. Raghunathan. Methyl 5-ferrocenyl-5a-hydr-oxy-1-methyl-10-oxo-2,3,3a,4,5a,10-hexa-hydro-1H indeno[1,2:2′,3′]furo[3′,4′-b]pyrrole-3a-carboxyl-ate. Acta Cryst. 2009, E65, 687-688.
5. S. Selvanayagam, B. Sridhar, K. Ravikumar, S. Kathiravan, R. Raghunathan. Methyl 2-(2,2,4-trimethyl-6-tosyl-perhydro-1,3-dioxino[5,4-c]pyridin-5-yl)acetate. Acta Cryst. 2009, E65, 1091.
4. E. T. S. Kamala, S. Nirmala, L. Sudha, S. Kathiravan, R. Raghunathan. Methyl 3-[ferrocen-yl(hydr-oxy)meth-yl]-1-methyl-2′-oxospiro-[pyrrolidine-2,3′-indoline]-3-carboxyl-ate. Acta Cryst. 2009, E65, 531-532.
3. B. Gunasekaran, S. Kathiravan, R. Raghunathan, V. Renuga, V. Manivannan.
Methyl 1-methyl-3-phenyl-1,2,3,3a,4,9b-hexa-hydro-benzo[f]chromeno[4,3-b] pyrrole-3a-carboxyl-ate. Acta Cryst. 2009, E65, 1033.
2. S. Selvanayagam, B. Sridhar, K. Ravikumar, S. Kathiravan, R. Raghunathan. 1-Vinyl-1H-indole-3-carbaldehyde. Acta Cryst. 2008, E64, 1163.
1. S. Kathiravan, R. Raghunathan. Synthesis of dispiroindano thiazolo [2,3-b]benzo[h]quinazoiline pyrrolidines through 1,3- dipolar cycloaddition reaction. Indian J. Chem. sect B, 2008, 47B, 1117-1119.
Peer reviewed chapters in scientific books:
1. S. Kathiravan, I. A. Nicholls. Chapter 3 ‘Rh-catalyzed five-membered heterocycles synthesis’ in Noble Metal Noble Value: Ru-, Rh-, Pd- Catalyzed Heterocycle Synthesis, Eds. Xiao-Feng Wu, Imperial College Press, 127-172, ISBN: 978-1-78326-923-5.
2. S. Kathiravan, I. A. Nicholls, I. A ‘Cobalt catalyzed (sp2) C-H activation reactions with multi-unsaturated substrates for five and six membered nitrogen heterocycles’ In Targets in Heterocyclic Systems, Vol-23, Eds. Orazio Antonio Attanasi
Refereed Conference contributions:
1. Iridium catalysed C-H activation indoles. 2nd Swedish Chemical Society National Meeting (SCS-2022), Linköping University, Sweden, June 20-22, 2018 (2022).
2. Electrooxidative amination of sp2 C-H bonds: Coupling of amines with aryl amides via copper catalysis. Abstracts of papers, 257th ACS National Meeting & Exposition, Orlando, Florida, USA. (2019)
3. Ruthenium catalysed decarboxylative alkylation. 1st Swedish Chemical Society National Meeting (SCS-2018), Lund University, Sweden, June 17-20, 2018 (2018).
4. Towards novel perfluoroalkylation of arenes. Abstracts of papers, 254th ACS National Meeting & Exposition, Washington, DC, USA. (2017)
5. Towards novel cobalt catalysed C-H activation strategies. Abstracts of papers, 253rd ACS National Meeting & Exposition, San Francisco, CA, USA. (2017)
6. Palldium-catlayzed decarboxylative vinyltrifluoromethylation of aryl halides. Abstracts of papers, 251stACS National Meeting & Exposition, San Diego, CA, USA. (2016)
7. Towards novel iridium based C-H activation strategies, Stockholm University, Sweden. (2016)
8. Rhodium catalyzed aerobic C(sp2)-C(sp) Dehydrogenative amino arylation of alkynes to highly functionalized indoles from N-aryl urea under mild conditions, Rennes, France. (2014)
9. Anti-Infective Drug Discovery and Development, held at Indian Institute of Technology, Chennai, India. (2011)
10. Presented a paper in an International level conference, 46th Annual convention of Chemist- International Conference on Recent Research Trends in Chemical Sciences held at VIT University, Vellore, India. (2009)
11. Presented paper in a National Symposium in Chemistry, NSC-11, held at NCL, Pune, India. (2009)
12. Presented a paper in a national level conference, “Recent Research Trends in Medicinal Chemistry, held at Stella Mari’s College, Chennai, India. (2008)
13. Presented a paper in a National Symposium in Chemistry, NSC-10, held at IISc Bangalore, India. (2008)
14. Presented a paper in a national level symposium, 4th Junior National Organic Symposium Trust 4th-JNOST, held at Madurai Kamaraj University, Tamil Nadu, India. (2008)
Graduate student supervision
Co-supervisor for Ph.D. students at Linnaeus University
3. Prakriti Dhillon (2020-2024) Linnaeus University, Proposed thesis title-Cobalt and ruthenium catalyzed C-H activation
2. Prasad Aanaspure (2018-2022) Linnaeus University, Thesis title-Novel strategies for C-C/X bond formation (No.470/2022)
1. Tianshu Zhang (2021-2022) Linnaeus University (Pre-doctoral research), Project title-Iridium catalyzed C-H activation of indoles (Currently PhD student in University of Santiago de Compostela (Spain).
Main Supervisor for M.Sc. students at Linnaeus University
8. Julia Wtulich (2023-2024), Erasmus student, 20 week, 30-credit examination Project title-Ruthenium catalysed C-H activation in deep eutectic solvents (DES)
7. Mohamed Hedi Belhaj (2021-2022), 40 week, 60 credit examination project, Thesis title-Copper and nickel catalyzed synthesis of 1,3-diynes and exploration of cobalt catalyzed C-H activation in unconventional solvent
6. Nazanin Hassanzzadeh (2020-2021), 40 week, 60-credit examination project, Thesis title-Suzuki reactions in novel liquids
5. Tianzhu Zhang (2020-2021), 40 week, 60-credit examination project, Thesis title-Copper(I) catalyzed click reaction in novel liquids
4. Ogechukwu Blessing Okereke (2019-2020), 40 week, 60-credit examination project, Thesis title-Synthesis, characterization and quantification of dipeptides in non-ionic deep eutectic solvents
3. Prakriti Dhillon– (2017-2018), 40 week, 60-credit examination project, Thesis title-Cobalt catalyzed, regioselective C-H activation of amides with unsymmetrical 1,3-diynes using 8-aminoquinoline as a bidendate directing group
2. Kleomenis Tsimpos– (2016-2017), 40 week, 60-credit examination project, Thesis title-Towards a synthetic tryptophan aminotransferase
1. Katharina-Sophie Görtemaker–2017, 15-credit examination project, Project title-Synthesis of unsymmetrical 1,3-diynes-For cobalt catalyzed, regioselective C-H activation of amides
Supervised M.Sc. students at the University of Madras
Supervised masters students – 2008-2011, (eight students, each undertaking six month projects)
Supervised master’s student’s practical classes– 2008-2011 (two semesters for each year)
Co-supervision of four PhD students over the first 12 months of their PhD training (with Prof. Raghavachary Raghunathan)
1. P. Madan Kumar – 2008 (Currently Assistant Professor-Mahendra Arts & Science College, Tamil Nadu, India)
2. D. Vijayarajan – 2009 (Currently senior chemist in Adesis Inc, USA)
3. P. Ashok Kumar – 2010 (Currently research scientist at Nuchem Sciences, Montreal, Canada)
4. P. Niranjana – 2010
Reviewer for many journals including Chem Commun., Org. Lett., J. Org. Chem., Org. Chem. Front., Int. J. Mol. Sci., Pharmaceutics, Molecules, Catalysts, Metals, Biomass, Molbank, and Antioxidants.
2016 American Chemical Society (ACS) Publications Reviewing Activity Award
1. Swedish Chemical Society Meeting, Linköping University, 2022
Title: Iridium catalyzed C-H activation of indoles
1. Member of the Swedish Chemical Society (SCS)
2. Member of the American Chemical Society (ACS)
3. Affiliate member of the Royal Society of Chemistry (RSc)
1. Prof. Ian A. Nicholls
Department of Chemistry and Biomedical Sciences
Linnaeus University
Kalmar - 39182
Email - ian.nicholls@lnu.se
Ph.No. 0480 44 6258
2. Dr. Teodor Aastrup
CEO of Attana AB
Greta Arwidssons Väg 21
114 19 Stockholm
Email - teodor.aastrup@attana.com